Carika WELDON (CariGenetics, Bermuda) : Nanopore Sequencing and Its Possibilities
Nanopore sequencing is a revolutionary technology that allows for the native sequencing of both DNA and RNA by analyzing changes in electrical current as molecules pass through partial nanopores in an artificial membrane.
Unlike traditional sequencing methods, nanopore sequencing enables real-time analysis of DNA or RNA without the need for amplification or chemical labeling, offering unparalleled speed and flexibility. Its portability, low cost, and high-throughput capacity to produce long-read sequences make it particularly suitable for applications in genomics, transcriptomics, and epigenomics.
This technology has unlocked possibilities in fields such as personalized medicine, pathogen surveillance, environmental monitoring, and evolutionary biology. The ability to perform in-field sequencing with devices like the MinION, GridION and PromethION empowers researchers to rapidly detect genetic variations, monitor outbreaks, and sequence genomes in remote locations.
Furthermore, advances in bioinformatics and nanopore chemistry are continuously improving the accuracy and sensitivity of the technology, expanding its applicability to challenging samples such as cellular free DNA, ancient DNA and FFPE DNA and RNA whilst also allowing for real-time targeted panels via adaptive sampling who allows the nanopore to only sequence for chosen regions of interest.
Come and meet us at room B308, on Fouillole campus (floor 3, research building)
Or participate via Zoom :
https://univ-antilles-fr.zoom.us/j/98840519507?pwd=bmwETsGrNOVldfRf5h1KzlKZkID4jG.1
Webinar ID : 988 4051 9507
Secret code : 575907